Common Side Effects

• The most common side effects of Daktarin involve your skin. Many patients who use the drug experience redness and irritation at the application site. Some patients also report burning or itching after applying the medication. Additionally, Daktarin frequently causes skin rashes. If you experience any of these side effects, you should talk to your doctor about switching to a different anti-fungal medication.
  
  

Other Side Effects

• Daktarin also has the potential to cause a number of other troublesome or annoying, but not dangerous, side effects. Possible gastrointestinal side effects of the drug include nausea, vomiting, diarrhea and lack of appetite. Some patients experience fever or chills while taking Daktarin.
  
  

Drug Interactions

• There are some medications which produce unwanted side effects when used in conjunction with Daktarin. When combined with blood thinners like Warfarin, Daktarin increases your risk of experiencing uncontrollable bleeding during surgery or following an injury. Additionally, nonsedative antihistamines like astemizole and terfenadine have the potential to cause cardiovascular side effects like arrhythmia when combined with Daktarin. In some cases, the combination leads to sudden, fatal cardiac arrest.
  
  

Allergic Reactions

• Some patients experience a hypersensitivity or allergic reaction to Daktarin. This reaction is typically anaphylactic in nature, meaning that it provokes an immune system response. Often, these reactions begin with hives or itching around the mouth, progressing to more serious symptoms. Daktarin-induced anaphylaxis can result in the inability to breathe, shock or even death. If you experience any signs of an allergic reaction at any point while using Daktarin, seek prompt emergency medical care. Additionally, you should notify your doctor before taking Daktarin if you have ever experienced an allergic reaction to a azole-type antifungal medication in the past.
  
  

Risks

• In addition to minor side effects and the risk of interactions, Daktarin has the potential to cause serious medical complications. Some patients develop a racing heartbeat or experience respiratory or heart failure while using the drug. Cardiovascular side effects are most common when dosage levels are increased too rapidly. Infrequently, Daktarin causes thrombocytopenia or a shortage of blood platelets, which can cause bleeding in your brain or lungs.