Robotic Navigation in Catheter Ablation for Paroxysmal Atrial Fibrillation
Robotic Navigation in Catheter Ablation for Paroxysmal Atrial Fibrillation
Robotic Navigation in Ablation of Paroxysmal AF. Introduction: Remote navigation systems represent a novel strategy for catheter ablation of atrial fibrillation (AF). The goal of this study is to describe a single-center experience with the electromechanical robotic system (Sensei, Hansen Medical) in treatment of patients with paroxysmal AF.
Methods: Out of 200 patients who underwent robotically guided ablation for AF between 2007 and 2009 at our institute, 100 patients (29 women, age 56.5 ± 10 years) had paroxysmal AF refractory to antiarrhythmic drugs. Electroanatomic mapping using NavX system (St. Jude Medical) provided anatomical shell for subsequent circumferential ablation with robotic catheter (Artisan) loaded with a 3.5-mm, open-irrigation, cooled-tip ablation catheter.
Results: A mean of 69 radiofrequency current applications (duration 2082 ± 812 seconds) were delivered to achieve circumferential electrical isolation of pulmonary venous antra. Total procedural time reached 222 ± 54 minutes. The mean fluoroscopic time was 11.9 ± 7.8 minutes. There were no major procedure-related complications. After a median follow-up of 15 months (range 3-28 months), 63% of the patients were free from any atrial arrhythmias ≥ 30 seconds after the single procedure. Success rate increased to 86% after 1.2 procedures. Multivariate analysis revealed that only predictor of recurrent AF/AT was shorter overall procedural time (207 ± 36 vs 236 ± 64 minutes in patients with and without recurrences, respectively, P = 0.0068).
Conclusions: This study demonstrates feasibility and safety of robotic navigation in catheter ablation for paroxysmal AF. Midterm follow-up documents success rate comparable to other technologies and potential for improvement in more extensive ablation along the ridges with thicker myocardium.
Catheter ablation has become an established treatment for atrial fibrillation (AF). Since the pioneering work by Haissaguerre et al., strategies focusing on electrical isolation of the pulmonary veins (PVs) have been developed. However, long-term success of the procedure is limited by a high rate of reconduction of previously isolated myocardial tissue. Due to individual anatomy of the PVs, ablation procedure is quite complex and requires specific skills. Last but not least, catheter ablation for AF is associated with prolonged fluoroscopy time and increased radiation dose, both for the patient and the operator. All these problems provide a rationale for the use of novel technologies that should achieve the goal more effectively and with less radiation risk. One of these strategies comprises remote navigation of the ablation catheter. Of the 2 available technologies, electromechanical system has been shown recently to provide safe navigation of catheter ablation with significant reduction of radiation dose. However, data about midterm efficacy of this approach are still limited. The goal of this study is to report a single-center experience on clinical outcome of robotically guided catheter ablation in a cohort of patients with paroxysmal AF.
Abstract and Introduction
Abstract
Robotic Navigation in Ablation of Paroxysmal AF. Introduction: Remote navigation systems represent a novel strategy for catheter ablation of atrial fibrillation (AF). The goal of this study is to describe a single-center experience with the electromechanical robotic system (Sensei, Hansen Medical) in treatment of patients with paroxysmal AF.
Methods: Out of 200 patients who underwent robotically guided ablation for AF between 2007 and 2009 at our institute, 100 patients (29 women, age 56.5 ± 10 years) had paroxysmal AF refractory to antiarrhythmic drugs. Electroanatomic mapping using NavX system (St. Jude Medical) provided anatomical shell for subsequent circumferential ablation with robotic catheter (Artisan) loaded with a 3.5-mm, open-irrigation, cooled-tip ablation catheter.
Results: A mean of 69 radiofrequency current applications (duration 2082 ± 812 seconds) were delivered to achieve circumferential electrical isolation of pulmonary venous antra. Total procedural time reached 222 ± 54 minutes. The mean fluoroscopic time was 11.9 ± 7.8 minutes. There were no major procedure-related complications. After a median follow-up of 15 months (range 3-28 months), 63% of the patients were free from any atrial arrhythmias ≥ 30 seconds after the single procedure. Success rate increased to 86% after 1.2 procedures. Multivariate analysis revealed that only predictor of recurrent AF/AT was shorter overall procedural time (207 ± 36 vs 236 ± 64 minutes in patients with and without recurrences, respectively, P = 0.0068).
Conclusions: This study demonstrates feasibility and safety of robotic navigation in catheter ablation for paroxysmal AF. Midterm follow-up documents success rate comparable to other technologies and potential for improvement in more extensive ablation along the ridges with thicker myocardium.
Introduction
Catheter ablation has become an established treatment for atrial fibrillation (AF). Since the pioneering work by Haissaguerre et al., strategies focusing on electrical isolation of the pulmonary veins (PVs) have been developed. However, long-term success of the procedure is limited by a high rate of reconduction of previously isolated myocardial tissue. Due to individual anatomy of the PVs, ablation procedure is quite complex and requires specific skills. Last but not least, catheter ablation for AF is associated with prolonged fluoroscopy time and increased radiation dose, both for the patient and the operator. All these problems provide a rationale for the use of novel technologies that should achieve the goal more effectively and with less radiation risk. One of these strategies comprises remote navigation of the ablation catheter. Of the 2 available technologies, electromechanical system has been shown recently to provide safe navigation of catheter ablation with significant reduction of radiation dose. However, data about midterm efficacy of this approach are still limited. The goal of this study is to report a single-center experience on clinical outcome of robotically guided catheter ablation in a cohort of patients with paroxysmal AF.