Health & Medical Women's Health

Essential Facts About Medical Abortion Pills

Mifepristone is a steroid that is used by most pharmaceuticals as an abortive method in ending the first trimester.
It usually attacks progesterone receptors and is therefore administered as an emergency contraceptive in smaller doses.
The manufacturing firm which designed this synthetic drug, also called RU-486, is under the supervision of Roussel Uclaf.
This so-called "abortion pill" was initially sold in France, followed by other countries.
Even in the midst of controversial issues, the marketing and dispensing of the product still goes on.
The abortion pill is marketed under trade names Korlym and Mifeprex.
Medical uses Mifepristone is mostly sold outside of the United States by Exelgyn Laboratories in France with names as Mifegyne, and is medically approved for the use of the following:
  • Medically, as a termination of intrauterine pregnancies up to 49 days of gestation or up to 63 days gestation in Europe particularly Sweden and Britain.
  • Prior to mechanical dilatation for pregnancy termination of the cervix it is use as a cervical softening and dilatation.
  • In 13 to 24 weeks gestation, it is mostly used in combination with gemeprost for termination of pregnancies.
  • Used to induce labor in cases of fetal death while inside the uterus.
Other uses of the drug As observed in Phase 2 clinical studies of this mifepristone, other clinical uses of the drug include oral contraception, treatment for endometriosis, glaucoma, uterine fibroids and meningiomas, plus breast, ovary, and prostate cancers.
The drug is also been found effective in treating Cushing's syndrome without side effects even after 10 years of administration.
Additionally, it is also observed to be effective in significantly addressing symptoms of pyshotic major depression, a form of depression resistant to conventional therapy.
Effects were immediate; however, the study was restricted by the small sample in very constricted duration of treatment.
FDA Controversy The existence of this abortion pill has been hounded by so much controversy and negative feedbacks.
In United States alone, many pro-life groups were actively protesting against its approval and more people were continuously crusading for its withdrawal.
Cited views were either on the ethical issues with the concept of abortion or on safety concerns with regard to the drugs adverse reactions to humans including death, which was then marked as "RU-486 Suspension and Review Act.
" Moreover, even religious and pro-life group outside the United States of America have also crusaded against the use of Mifepristone more specifically in Germany and Australia.
Consequently, proper administration of this drug should be supported by a medical specialist.


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